Ontario Cancer Research Ethics Board

The Ontario Cancer Research Ethics Board (OCREB) is a program of the Ontario Institute for Cancer Research (OICR). OCREB is an innovative, oncology-specialized Research Ethics Board (REB) serving hospitals in Ontario that conduct cancer clinical trials. OCREB’s centralized model streamlines the review process, minimizes redundancy, promotes consistency, and saves the time and cost of having the study reviewed by an REB at every participating institution (study site).

OCREB is a respected and consulted leader in research ethics and was the first REB to be qualified through the Clinical Trials Ontario (CTO) REB Qualification program. Although it is independent in its decisions and operates at arm’s length from programmatic and research structures within OICR, OCREB is accountable to the OICR Board of Directors through the Governance Committee and the OCREB Advisory Committee.

Recent Announcments

July 3, 2026

New Main/Optional ICF Template and Treatment Beyond Disease Progression Signature Page Template available now.

June 17, 2026

New Participant Reimbursement Guidelines & Genetic Non-Discrimination Act (GNDA) Guidance for OCREB Reviewers available

June 10, 2026

New Pediatric Memos regarding changes in consenting practices and team-based consenting available

June 1, 2026

New French Wallet Card Template and COT now available. Click to view more detail on Guidelines & Templates

COMING SOON !

Click to sign up for OCREB 101 Training

Metrics

Call for Members

OCREB’s stellar membership is gathered from around Ontario to provide both expertise and a variety of perspectives. To meet the challenges of multi-centre oncology clinical trials, OCREB’s members include medical and radiation oncologists, advanced practice and clinical trial nurses, clinical research coordinators, informed community members and cancer survivors, and experts in epidemiology, bioethics, statistics, pharmacology and law.

OCREB Members at an all-board meeting.

Participating Sites

Participating Sites
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